For the first four years of my career I was never less than an hour's drive away from work (at least two hours round trip). This lead to a mass consumption of and undying love for podcasts. Below you'll find my current favorites. If you have any good recommendations send them my way!
If you want to know exactly what's going through a hacker's mind the minute before they break through your code you've gotta give this a listen.
If you want to know exactly what's going on with humans in space hit this up. It's more fact than story-telling but it has some pretty cool astronaut interviews and goes through space policy in the US.
Ministry of Testing
How can this not be a favorite! Richard Bradshaw and Mark Winteringham run this podcast and they are wonderful and quirky hosts. If you're looking to hear from more people in the test community THIS IS THE PLACE.
Women at Warp
ANDI, GRACE, JARRAH, & SUE
Fancy yourself a trekkie and a feminist? You can be both! This podcast has four of them.